Data Supplement
- Supplemental Data -
Supplementary Figure 1 - Workflow for isolation of total membranes from the placental tissues (A) followed by quantitative targeted proteomics (B).
Supplementary Table 1 - Surrogate peptides and LC-MS/MS parameters for quantification of placental drug transporters and membrane markers.
Supplementary Table 2 - LC conditions for surrogate peptide quantification.
Supplementary Table 3 - Placentae donor demographics.
Supplementary Figure 2 - Placental sites (A) used in the analyses of site-dependent (B) and inter-day variability (C) of transporter abundance in three T2 placentae.
Supplementary Figure 3 - Protein abundance of apical and basal membrane transporters in human placentae of three gestational ages.
Supplementary Table 4 - Protein abundance of apical and basal membrane transporters in human placentae of three gestational ages.
Supplementary Figure 4 - Comparison of transporter protein abundance in human placenta, kidney and liver as measured by quantitative targeted proteomics.
Supplementary References
Supplementary Figure 5 - Protein-protein correlation of placental transporter abundance (N=49).