Data Supplement
- Supplemental Data -
Supplementary Methods
Supplementary Table 1 - Primers and oligos sequences.
Supplementary Table 2 - Analytical conditions for test compounds.
Supplementary Table 3 - Batch differences in the quality of monkey BMECs (MBT-24H).
Supplementary Figure 1 - YM155 uptake in HEK293 cells stably expressing hSLC35F2 and mSLC35F2.
Supplementary Figure 2 - SLC35F2 expression and localization in control and SLC35F2 knockout PC-3 cells.
Supplementary Figure 3 - Inhibitory effects of cationic drugs on YM155 uptake mediated by SLC35F2 in control PC-3 cells.
Supplementary Figure 4 - Investigation of SLC35F2 substrate drugs and driving force.
Supplementary Figure 5 - Quality validation of monkey BMECs (related to Figure 3).
Supplementary Figure 6 - Quality validation of hiPS-BMECs (related to Figure 4).
Supplementary Figure 7 - Quality validation of SLC35F2 KO hiPS-BMECs (related to Figure 5).
Supplementary Figure 8 - YM155 uptake mediated by mouse OATP1A4 and human OATP1A2 (related to Figure 6).