Disposition and Metabolism of [¹⁴C]Lemborexant in Healthy Human Subjects and Characterization of Its Circulating Metabolites

Data Supplement

• Supplemental Data -

  Supplementary Data

  Supplementary Table 1 - Molecular ions and characteristic fragment ions of lemborexant and metabolites detected in biological samples.

  Supplementary Figure 1  - Chemical structure of [14C]lemborexant. Asterisk denotes the position of the 14C label.

  Supplementary Figure 2 - Representative HPLC radiochromatograms of metabolites in human plasma, urine, and feces.