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OtherArticle

Simultaneous evaluation of membrane permeability and UDP-glucuronosyltransferase-mediated metabolism of food-derived compounds using human induced pluripotent stem cell-derived small intestinal epithelial cells

Takashi Kitaguchi, Taisei Mizota, Mina Ito, Katsutoshi Ohno, Kazuhiro Kobayashi, Isamu Ogawa, Shimeng Qiu, Takahiro Iwao, Nobumitsu Hanioka, Mitsuru Tanaka and Tamihide Matsunaga
Drug Metabolism and Disposition October 20, 2021, DMD-AR-2021-000605; DOI: https://doi.org/10.1124/dmd.121.000605
Takashi Kitaguchi
1Global Food Safety Institute, Nissin Foods Holdings Co., Ltd., Japan
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  • For correspondence: takashi.kitaguchi@nissin.com
Taisei Mizota
1Global Food Safety Institute, Nissin Foods Holdings Co., Ltd., Japan
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Mina Ito
1Global Food Safety Institute, Nissin Foods Holdings Co., Ltd., Japan
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Katsutoshi Ohno
1Global Food Safety Institute, Nissin Foods Holdings Co., Ltd., Japan
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Kazuhiro Kobayashi
1Global Food Safety Institute, Nissin Foods Holdings Co., Ltd., Japan
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Isamu Ogawa
2Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
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Shimeng Qiu
2Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
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Takahiro Iwao
3Nagoya City University, Japan
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Nobumitsu Hanioka
4Department of Health Pharmacy, Yokohama University of Pharmacy, Japan
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Mitsuru Tanaka
1Global Food Safety Institute, Nissin Foods Holdings Co., Ltd., Japan
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Tamihide Matsunaga
2Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan
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Data Supplement

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    Pathway and transporter susceptibility during intestinal absorption and reported F a or F a F g values in humans of 21 tested drugs.

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