PT  - JOURNAL ARTICLE
AU  - Waring, R H
AU  - Mitchell, S C
TI  - The metabolism and elimination of S-carboxymethyl-L-cysteine in man.
DP  - 1982 Jan 01
TA  - Drug Metabolism and Disposition
PG  - 61--62
VI  - 10
IP  - 1
4099  - http://dmd.aspetjournals.org/content/10/1/61.short
4100  - http://dmd.aspetjournals.org/content/10/1/61.full
SO  - Drug Metab Dispos1982 Jan 01; 10
AB  - The metabolism of 14C- and 35S-labeled S-carboxymethylcysteine (SCMC) has been compared. The majority of the dose appeared in urine in the first 24 hr; no activity was detectable in feces. Use of 25S-labeled compound gave small amounts of inorganic 35S-sulfate, whereas 14C-labeled material was degraded to give some [14C]urea. Peak excretion of the parent compound occurred first after administration of SCMC; metabolites requiring one chemical modification for their formation were maximally excreted 1-4 hr after the dose and those involving more metabolic processes appeared later (4-8 hr).