TY - JOUR T1 - New aspects of metabolic conjugation of chloramphenicol. JF - Drug Metabolism and Disposition JO - Drug Metab Dispos SP - 635 LP - 639 VL - 16 IS - 4 AU - J M Wal AU - J C Peleran AU - E Perdu AU - D Rao AU - G Bories Y1 - 1988/07/01 UR - http://dmd.aspetjournals.org/content/16/4/635.abstract N2 - New and major chloramphenicol (CP) metabolites have been isolated from the urine of goats administered [3H]CP. The CP-3-sulfoconjugate has been identified formally from its chromatographic behaviour and mass spectrometric analysis, as well as from incubations of CP with liver cytosol, using synthetic CP-conjugate as reference. Only a strong assumption is made of the identity of the CP-3-phosphoconjugate. ER -