RT Journal Article
SR Electronic
T1 Inhibition of human red blood cell N-acetyltransferase.
JF Drug Metabolism and Disposition
JO Drug Metab Dispos
FD American Society for Pharmacology and Experimental Therapeutics
SP 181
OP 183
VO 21
IS 1
A1 R A Voice
A1 M Manis
A1 W W Weber
YR 1993
UL http://dmd.aspetjournals.org/content/21/1/181.abstract
AB Acetanilide and derivatives of benzoic acid, benzamide, salicylic acid, and salicylamide were tested as inhibitors of p-aminobenzoic acid N-acetyltransferase partially purified from peripheral blood of three rapid and two slow dapsone acetylator human volunteers. The 50% inhibition point of these compounds does not provide a kinetic basis for differentiating the rapid and slow dapsone acetylator phenotypes.