PT  - JOURNAL ARTICLE
AU  - MARCUS M. REIDENBERG
AU  - JOHN H. MARTIN
TI  - THE ACETYLATOR PHENOTYPE OF PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
DP  - 1974 Jan 01
TA  - Drug Metabolism and Disposition
PG  - 71--73
VI  - 2
IP  - 1
4099  - http://dmd.aspetjournals.org/content/2/1/71.short
4100  - http://dmd.aspetjournals.org/content/2/1/71.full
SO  - Drug Metab Dispos1974 Jan 01; 2
AB  - Because patients developing systemic lupus erythematosus after taking hydralazine have been shown to be genetic slow acetylators, we determined the acetylator phenotype of 14 patients with spontaneous systemic lupus erythematosus. Ten were unequivocally slow acetylators, one was probably slow, one was indeterminate by our method of phenotyping using dapsone, and two were rapid acetylators. This predominance of slow acetylators is different from the expected even distribution of slow and rapid acetylators in the population. Copyright © 1974 by The American Society for Pharmacology and Experimental Therapeutics