RT Journal Article
SR Electronic
T1 Current Progress on Esterases: From Molecular Structure to Function
JF Drug Metabolism and Disposition
JO Drug Metab Dispos
FD American Society for Pharmacology and Experimental Therapeutics
SP 488
OP 493
DO 10.1124/dmd.30.5.488
VO 30
IS 5
A1 Satoh, Tetsuo
A1 Taylor, Palmer
A1 Bosron, William F.
A1 Sanghani, Sonal P.
A1 Hosokawa, Masakiyo
A1 Du, Bert N. La
YR 2002
UL http://dmd.aspetjournals.org/content/30/5/488.abstract
AB This article reports on a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics and held at the April 2001 Experimental Biology meeting. Current developments in molecular-based studies into the structure and function of cholinesterases, carboxylesterases, and paraoxonases are described. This article covers mechanisms of regulation of gene expression of the various esterases by developmental factors and xenobiotics, as well as the interplay between physiological and chemical regulation of enzyme activity. The American Society for Pharmacology and Experimental Therapeutics