PT  - JOURNAL ARTICLE
AU  - Wells, Peter G.
AU  - Mackenzie, Peter I.
AU  - Roy Chowdhury, Jayanta
AU  - Guillemette, Chantal
AU  - Gregory, Philip A.
AU  - Ishii, Yuji
AU  - Hansen, Antony J.
AU  - Kessler, Fay K.
AU  - Kim, Perry M.
AU  - Roy Chowdhury, Namita
AU  - Ritter, Joseph K.
TI  - GLUCURONIDATION AND THE UDP-GLUCURONOSYLTRANSFERASES IN HEALTH AND DISEASE
AID  - 10.1124/dmd.32.3.281
DP  - 2004 Mar 01
TA  - Drug Metabolism and Disposition
PG  - 281--290
VI  - 32
IP  - 3
4099  - http://dmd.aspetjournals.org/content/32/3/281.short
4100  - http://dmd.aspetjournals.org/content/32/3/281.full
SO  - Drug Metab Dispos2004 Mar 01; 32
AB  - This article is an updated report of a symposium held at the June 2000 annual meeting of the American Society for Pharmacology and Experimental Therapeutics in Boston. The symposium was sponsored by the ASPET Divisions for Drug Metabolism and Molecular Pharmacology. The report covers research from the authors' laboratories on the structure and regulation of UDP-glucuronosyltransferase (UGT) genes, glucuronidation of xenobiotics and endobiotics, the toxicological relevance of UGTs, the role of UGT polymorphisms in cancer susceptibility, and gene therapy for UGT deficiencies. The American Society for Pharmacology and Experimental Therapeutics