RT Journal Article SR Electronic T1 GLUCURONIDATION AND THE UDP-GLUCURONOSYLTRANSFERASES IN HEALTH AND DISEASE JF Drug Metabolism and Disposition JO Drug Metab Dispos FD American Society for Pharmacology and Experimental Therapeutics SP 281 OP 290 DO 10.1124/dmd.32.3.281 VO 32 IS 3 A1 Peter G. Wells A1 Peter I. Mackenzie A1 Jayanta Roy Chowdhury A1 Chantal Guillemette A1 Philip A. Gregory A1 Yuji Ishii A1 Antony J. Hansen A1 Fay K. Kessler A1 Perry M. Kim A1 Namita Roy Chowdhury A1 Joseph K. Ritter YR 2004 UL http://dmd.aspetjournals.org/content/32/3/281.abstract AB This article is an updated report of a symposium held at the June 2000 annual meeting of the American Society for Pharmacology and Experimental Therapeutics in Boston. The symposium was sponsored by the ASPET Divisions for Drug Metabolism and Molecular Pharmacology. The report covers research from the authors' laboratories on the structure and regulation of UDP-glucuronosyltransferase (UGT) genes, glucuronidation of xenobiotics and endobiotics, the toxicological relevance of UGTs, the role of UGT polymorphisms in cancer susceptibility, and gene therapy for UGT deficiencies. The American Society for Pharmacology and Experimental Therapeutics