PT - JOURNAL ARTICLE AU - Murphy, Patrick J. TI - The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 2, 1959–1983 AID - 10.1124/dmd.108.021113 DP - 2008 Jun 01 TA - Drug Metabolism and Disposition PG - 981--985 VI - 36 IP - 6 4099 - http://dmd.aspetjournals.org/content/36/6/981.short 4100 - http://dmd.aspetjournals.org/content/36/6/981.full SO - Drug Metab Dispos2008 Jun 01; 36 AB - In 25 years, drug metabolism research went from using subcellular particles of undefined content to an understanding of metabolism at the molecular level. The discoveries of cytochrome P450, enzyme induction, reactive intermediates, and genetic polymorphisms were milestones in the field. New publications from the American Society for Pharmacology and Experimental Therapeutics chronicled the discoveries and provided communications to advance the science of drug metabolism. The American Society for Pharmacology and Experimental Therapeutics