TY - JOUR T1 - N-Didemethyl-n-propionyl-6,9;9, 12-erythromycin A-spiroketal, a new metabolite of erythromycin ethyl succinate in man. JF - Drug Metabolism and Disposition JO - Drug Metab Dispos SP - 673 LP - 676 VL - 6 IS - 6 AU - J Majer AU - R S Stanaszek AU - S L Mueller AU - G Marti Y1 - 1978/11/01 UR - http://dmd.aspetjournals.org/content/6/6/673.abstract N2 - A novel, neutral metabolite of erythromycin was isolated from the urine of a patient treated with erythromycin ethyl succinate. After separation and purification on Sephadex LH-20 column chromatography, the structure of the metabolite was deduced from spectral data to be the propionamide of the didemethylated 6,9;9, 12-spiroketal of erythromycin A. ER -