PT  - JOURNAL ARTICLE
AU  - Kutzman, R S
AU  - Meyer, G J
AU  - Wolf, A P
AU  - Akasaka, T
TI  - The biodistribution and metabolic fate of inhaled 11C-octanal in the rat after acute exposure.
DP  - 1981 Jul 01
TA  - Drug Metabolism and Disposition
PG  - 331--333
VI  - 9
IP  - 4
4099  - http://dmd.aspetjournals.org/content/9/4/331.short
4100  - http://dmd.aspetjournals.org/content/9/4/331.full
SO  - Drug Metab Dispos1981 Jul 01; 9
AB  - Rats were nose exposed to an atmosphere containing 11.4 ppm of 11C-octanal for 2 min. Inhaled octanal was absorbed from the lungs in a biphasic manner and the greatest concentration of octanal occurred in most tissues at 5 min. Tissue activities calculated on the basis of the administered dose and on the radiolabel retained until the animal was killed indicated a redistribution of the radiolabel as metabolic products after 20 min. The labeled carbon was eliminated in a biphasic manner as 11CO2, which accounted for essentially all of the activity lost by the exposed rats.