Table 3

Probe substrates for human UGTs

UGT-1 Subfamily (Chromosome 2q37)UGT-2 Subfamily (Chromosome 4q13)
EnzymeSubstrateEnzymeSubstrate
UGT1A1BilirubinUGT2B4Hyodeoxycholic acid
UGT1A4ImipramineUGT2B7Morphine
UGT1A61-NaphtholUGT2B15Androstanediol
UGT1A83-a Propofol
  • 3-a Nomenclature from Burchell laboratory. The same gene is designated UGT1A9 in the Tukey laboratory.