Estimation of OLZ and its metabolites in a urine sample3-a
Compound | % Urinary Radioactivity |
---|---|
10-N-glucuronide | 28.6 |
OLZ | 17.7 |
2-Carboxy OLZ | 5.2 |
N-Oxide OLZ | 3.9 |
N-Desmethyl OLZ | 0.8 |
Total 56.2 |
↵3-a Estimate is based on aqueous and ethyl acetate extracts of a urine sample from subject 1 (8–16 hr postdose).