Compounds | Drug Concentrations | ||||
---|---|---|---|---|---|
Liver | Intestine | Kidney | Lungs | Control | |
nmol/mg of protein | |||||
TNP-470 | 9.3 | 82.3 | 120.5 | 238.8 | 283.5 |
M-I | 35.6 | 0.0 | 25.6 | 0.0 | 0.0 |
M-II | 9.4 | 5.9 | 126.8 | 0.0 | 0.0 |
M-III | 28.0 | 0.0 | 0.0 | 0.0 | 0.0 |
M-IV | 260.0 | 254.1 | 68.4 | 103.5 | 58.8 |
Each value represents the mean of two independent experiments.