Table 2

Effects of DBSP, TCA, octreotide, and PAH on K_p values in SDRs and K_p values in EHBRs of [¹⁴C]octreotide and [³H]inulin 5 min after intravenous bolus injection of [¹⁴C]octreotide and [³H]inulin

	Control	DBSP	TCA	octreotide	PAH	EHBR
[¹⁴C]Octreotide
Liver	2.417 ± 0.140	0.466 ± 0.010^2-a	0.453 ± 0.094^2-a	1.235 ± 0.280^2-a	2.340 ± 0.326	0.692 ± 0.023^2-a
Kidney	5.263 ± 0.219	4.996 ± 0.093	4.402 ± 0.178	3.600 ± 1.773	3.815 ± 0.304^2-a	4.681 ± 0.472
Intestine	0.279 ± 0.007	0.237 ± 0.002^2-a	0.234 ± 0.002^2-a	0.262 ± 0.014	0.266 ± 0.008	0.230 ± 0.020
Pancreas	0.375 ± 0.075	0.300 ± 0.015	0.270 ± 0.007	0.186 ± 0.006	0.336 ± 0.020	0.287 ± 0.028
Lung	0.661 ± 0.010	0.581 ± 0.008^2-a	0.556 ± 0.017^2-a	0.643 ± 0.042	0.616 ± 0.018	0.575 ± 0.005^2-a
Muscle	0.153 ± 0.037	0.104 ± 0.001	0.097 ± 0.006	0.125 ± 0.034	0.127 ± 0.002	0.110 ± 0.009
Spleen	0.287 ± 0.005	0.276 ± 0.005	0.270 ± 0.035	0.328 ± 0.030	0.315 ± 0.006^2-a	0.289 ± 0.009
Cerebrum	0.011 ± 0.000	0.010 ± 0.000	0.010 ± 0.001	0.009 ± 0.000	0.012 ± 0.001	0.011 ± 0.000
Cerebellum	0.014 ± 0.001	0.014 ± 0.000	0.013 ± 0.001	0.014 ± 0.001	0.017 ± 0.000	0.015 ± 0.001
[³H]Inulin
Liver	0.171 ± 0.007	0.173 ± 0.007	0.206 ± 0.012	0.156 ± 0.009	0.179 ± 0.004	0.173 ± 0.011
Kidney	9.201 ± 1.407	8.141 ± 0.949	9.406 ± 0.297	7.380 ± 4.913	6.865 ± 0.402	12.033 ± 2.763
Intestine	0.214 ± 0.012	0.235 ± 0.007	0.255 ± 0.009^2-a	0.195 ± 0.031	0.221 ± 0.008	0.238 ± 0.023
Pancreas	0.250 ± 0.008	0.224 ± 0.009	0.226 ± 0.024	0.221 ± 0.016	0.235 ± 0.026	0.226 ± 0.003
Lung	0.431 ± 0.017	0.425 ± 0.007	0.429 ± 0.002	0.373 ± 0.037	0.401 ± 0.027	0.367 ± 0.069
Muscle	0.166 ± 0.007	0.182 ± 0.004	0.169 ± 0.009	0.094 ± 0.019^2-a	0.214 ± 0.012^2-a	0.275 ± 0.049
Spleen	0.195 ± 0.013	0.199 ± 0.012	0.206 ± 0.028	0.191 ± 0.017	0.193 ± 0.008	0.236 ± 0.017
Cerebrum	0.022 ± 0.002	0.024 ± 0.002	0.023 ± 0.001	0.020 ± 0.002	0.020 ± 0.001	0.021 ± 0.001
Cerebellum	0.024 ± 0.001	0.026 ± 0.001	0.025 ± 0.001	0.022 ± 0.001	0.022 ± 0.001	0.025 ± 0.002

↵2-a Significant diference from control (p < 0.05).