Estimation of metabolite recovery in urine and feces
| Component | % Dose in Urine2-a | % Dose in Feces2-b | Total % Dose |
|---|---|---|---|
| CZ | 0.5 | 2.0 | 2.5 |
| 1 | 7.0 | —c | 7.0 |
| 3 | 2.0 | 2.2 | 4.2 |
| 5 | 6.8 | —c | 6.8 |
| 6 | 11.1 | —c | 11.1 |
| 7 | —c | 3.1 | 3.1 |
| 8 | 5.1 | 1.8 | 6.9 |
| 9 | 1.1 | 0.2 | 1.3 |
| Total | 33.6 | 9.3 | 43.9 |
↵2-a 92% of the urinary radioactivity in the 0–72 hr time interval (43% of the dose) was committed to analysis; unidentified metabolites accounted for 9% of the dose.
↵2-b 95% of the fecal radioactivity in the 0–144 hr time interval (28% of the dose) was committed to extraction (13% of the dose remained in the fecal residue); unidentified metabolites represented 6% of the dose.