Microsomal scaling factors determined in UT, PB-treated, and DEX-treated rats
| CYP Content of Liver | CYP Content of Microsomes | Microsomal Scaling Factor3-a | |
|---|---|---|---|
| nmol/g | nmol/mg | mg/g liver | |
| UT | 49.7 ± 6.8 | 0.8 ± 0.1 | 60.1 |
| PB | 71.5 ± 9.3* | 1.5 ± 0.2** | 46.6** |
| DEX | 38.9 ± 7.1 | 0.8 ± 0.2 | 46.9* |
Data are presented as means ± SD (N = 4). Mean significantly different from UT (* p < 0.05, ** p < 0.01).
↵3-a Microsomal scaling factor calculated from the liver/microsome ratio of CYP.