Table 3

Microsomal scaling factors determined in UT, PB-treated, and DEX-treated rats

CYP Content of LiverCYP Content of MicrosomesMicrosomal Scaling Factor3-a
nmol/g nmol/mg mg/g liver
UT49.7  ± 6.80.8  ± 0.160.1
PB71.5  ± 9.3* 1.5  ± 0.2** 46.6**
DEX38.9  ± 7.10.8  ± 0.246.9*
  • Data are presented as means ± SD (N = 4). Mean significantly different from UT (* p < 0.05, ** p < 0.01).

  • 3-a Microsomal scaling factor calculated from the liver/microsome ratio of CYP.