Table 1

Plasma AT equivalent concentrations in mice after oral administration of 200 mg/kg of [14C]AT on days 1 and 14

TimeDay 1Day 14
hr μg-equiv/ml
PredoseBLQBLQ
149.029.8
227.82.40
48.702.75
84.744.64
122.211.06
AUC(0–12) 1-a 140.262.7

  • BLQ, below the limit of quantitation, twice background.

  • ↵1-a AUC, area under plasma concentration-time curve from 0 to 12 hours (μg · hr/ml).