Table 3

Urinary and fecal recovery in mice after oral administration of 200 mg/kg dose of [14C]AT on days 1 and 14

Time IntervalDay 1Day 14
UrineFecesUrineFeces
hr %
PredoseBLQ3-a BLQBLQBLQ
  0–241.0670.61.0293.5
 24–480.3226.50.114.01
 48–720.080.940.020.30
 72–960.020.240.010.18
 96–1200.010.05BLQ0.05
120–144BLQ0.02BLQ0.03
Total1.4998.41.1698.1
  • 3-a BLQ, below the limit of quantitation; twice background.