Table 2

Rate of nirvanol formation from (S)-MP (200 μM) by pooled HLMs and recombinant P450 isoforms

	Rate of Nirvanol Formation
	pmol/min/mg protein
Pooled HLMs	481.4
Recombinant P450 isoforms
1A2	NA^2-a
2B6	43.6
2C9	12.0
2C19	NA
2D6	NA
2E1	NA
3A4	NA

↵2-a NA, not active.