Table 2

Animal body weight, liver weight, microsomal protein, and liver P-450 content (mean ± S.D.) in dogs that are poor and extensive metabolizers of celecoxib

PopulationBody WeightLiver WeightMicrosomal ProteinP-450 Content
g g mg/g liver nmol P-450/mg protein
PM (n = 9)9.98  ± 1.34282  ± 4719.3  ± 2.60.521  ± 0.072
EM (n = 6)10.5  ± 0.5281  ± 2619.2  ± 1.60.506  ± 0.041