Literature data of apparent first order half-lives of 1-O-acylglucuronides of various drugs measured during incubation experiments in aqueous buffer of pH 7.4 at 37°C
| Compound | T1/2 | Reference |
|---|---|---|
| h | ||
| Tolmetin | 0.26 | (Fenselau, 1994) |
| Isoxepac | 0.29 | (Spahn-Langguth and Benet, 1992) |
| Probenecid | 0.4 | (Fenselau, 1994) |
| Zenarestat | 0.42 | (Tanaka and Suzuki, 1994) |
| Zomepirac | 0.45 | (Fenselau, 1994) |
| Diclofenac | 0.51 | |
| Diflunisal | 0.67 | (Williams and Dickinson, 1994) |
| Naproxen, R enantiomer | 0.92 | (Bischer et al., 1995) |
| Salicylic acid | 1.3 | (Liu et al., 1996) |
| Indomethacin | 1.4 | (Fenselau, 1994) |
| Naproxen, S enantiomer | 1.8 | (Bischer et al., 1995) |
| Ibuprofen | 3.3 | (Hayball, 1995) |
| Bilirubin | 4.4 | (Spahn-Langguth and Benet, 1992) |
| Furosemide | 5.3 | (Fenselau, 1994) |
| Flufenamic acid | 7 | (Fenselau, 1994) |
| Clofibric acid | 7.3 | (Fenselau, 1994) |
| Mefenamic acid | 16.5 | (McGurk et al., 1996) |
| Telmisartan | 26 | |
| Gemfibrozil | 44 | (Sallustio and Foster, 1995) |
| Valproic acid | 79 | (Fenselau, 1994) |