Table 1

Pharmacokinetics of indinavir in control and DEX-treated rats after i.v. administration of 10 mg/kg (mean ± S.D., n = 4)

TreatmentClVdssT1/2
ml/min/kg liter/kg min
Control100  ± 21.12.2  ± 0.4625.1  ± 11.3
DEX135  ± 36.12.5  ± 1.016.2  ± 8.6
Statistical analysisN.S.1-a N.S.1-a N.S.1-a

  • ↵1-a Not significant.