Table 2

Absorption kinetics of indinavir in control and DEX-treated rats after oral administration of 20 mg/kg (mean ± S.D., n = 4–5)

Treatment	C_max^2-a	T_max^2-b	AUC	F^2-c
	μM	min	μM · h	%
Control	2.8 ± 1.0	30 ± 0.0	1.85 ± 0.59	28.0
DEX	0.28 ± 0.06	66 ± 21	0.61 ± 0.33	12.4
Statistical analysis	p < .001	p < .05	p < .001

↵2-a Peak concentration.
↵2-b Time to reach peak concentration.
↵2-c Bioavailability (F) was estimated from the mean AUCs after i.v. and p.o. administration, correcting for the dose.