Table 4

Effect of DEX on the intestinal and hepatic metabolism of testosterone (500 μM) in rats (mean ± S.D., n = 3)

Microsomes	Treatment	Testosterone
Microsomes	Treatment	2β-Hydroxylation	6β-Hydroxylation
		pmol/min/mg protein
Liver	Control	64.0 ± 13.7	722 ± 132
	DEX-treated	736 ± 123^4-a	5011 ± 454^4-a
Intestine	Control	0.667 ± 0.104	16.3 ± 0.6
	DEX-treated	2.40 ± 0.78^4-a	50.9 ± 3.3^4-a

↵4-a Significantly different between control and DEX-treated rats at p < .001.