Table 2

Contents of total CYP and individual CYP forms in liver microsomes of 16 Japanese and 8 Caucasian samples

Human Sample No.	Total CYP^2-a	Individual CYP Enzymes^2-b
Human Sample No.	Total CYP^2-a	1A2	2A6	2B6	2C	2D6	2E1	3A	Sum^2-c
	nmol/mg protein	% of total CYP
J-1	0.11	8	0.4	0.2	21	0.5	9	19	58
J-2	0.14	11	0.3	0.1	24	1	4	47	88
J-3	0.15	2	0.3	nd	15	0.4	1	25	45
J-4	0.55	4	0.1	5	20	0.8	3	45	78
J-5	0.17	9	0.3	nd	34	0.9	5	18	67
J-6	0.19	6	8	0.1	35	0.8	7	31	88
J-7	0.33	18	3	2	21	0.4	5	35	85
J-8	0.05	30	1	1	26	2	4	32	95
J-9	0.48	14	1	0.1	20	1	4	26	65
J-10	0.23	9	14	1	15	1	6	47	92
J-19	0.09	11	2	nd	10	4	2	27	56
J-20	0.13	5	0.4	0.3	32	2	5	50	95
J-21	0.04	20	2	0.1	55	6	5	33	121
J-22	0.07	4	0.3	nd	27	1	3	13	48
J-23	0.19	9	0.5	nd	33	2	9	16	70
J-24	0.23	7	0.1	nd	30	2	9	14	61
Mean	0.20	10	2	0.6	26	2	5	30	76
± S.D.	0.15	7	4	1	11	2	2	12	20
C-11	0.52	7	4	2	16	1	31	17	78
C-12	0.50	9	4	4	20	1	31	16	87
C-13	0.55	6	4	9	17	2	4	26	67
C-14	0.35	13	5	0.5	23	2	9	23	76
C-15	0.28	23	2	0.2	25	2	5	20	78
C-16	0.31	16	4	0.2	18	2	5	17	62
C-17	0.27	16	1	nd	10	3	12	14	56
C-18	0.35	13	9	1	8	2	6	27	66
Mean	0.39	13	4	2	17	2	13	20	71
± S.D.	0.11	6	2	3	6	0.7	12	5	10

nd, not detectable.
↵2-a Spectrally determined CYP (nmol/mg protein).
↵2-b Immunochemically determined CYP (% of total CYP).
↵2-c Sum of immunochemically determined CYP (% of total CYP).