Time After Dose | i.v. | Oral | ||
---|---|---|---|---|
LSC | ELISA | LSC | ELISA | |
h | ng · ml−1 | ng · ml−1 | ng · ml−1 | ng · ml−1 |
0.5 | 7.8 (2.8) | 7.9 (4.2) | 24.2 (10.8) | 21.0 (6.5) |
1 | 14.0 (6.7) | 12.6 (6.7) | 38.1 (8.3) | 32.3 (15.1) |
1.5 | 33.6 (14.8) | 29.4 (17.0) | ||
2 | 16.3 (5.7) | 15.9 (6.2) | 30.3 (17.6) | 25.7 (17.5) |
3 | 21.1 (13.6) | 16.8 (12.4) | ||
4 | 23.5 (6.1) | 22.8 (6.4) | 15.5 (11.9) | 13.8 (11.5) |
4.08 | 21.7 (6.3) | 20.1 (5.3) | ||
4.25 | 19.0 (4.9) | 18.5 (5.8) | ||
4.5 | 17.0 (4.5) | 15.8 (3.9) | ||
4.75 | 15.0 (2.8) | 14.5 (3.4) | ||
5 | 13.1 (3.4) | 12.6 (4.0) | 12.3 (6.6) | 10.2 (8.1) |
6 | 9.2 (1.7) | 9.8 (2.2) | 10.0 (7.1) | 8.4 (6.2) |
8 | 7.0 (1.0) | 7.4 (1.9) | 8.3 (5.1) | 6.0 (4.7) |
10 | 5.8 (1.0) | 6.2 (1.5) | 6.4 (4.9) | 5.6 (3.9) |
12 | 5.4 (1.1) | 5.2 (1.6) | 5.8 (3.7) | 4.9 (3.5) |
14 | 5.5 (1.6) | 5.0 (1.7) | 4.3 (6.8) | 4.4 (3.0) |
16 | 5.0 (1.2) | 4.5 (1.1) | 4.1 (3.3) | 4.3 (2.8) |
20 | 4.6 (2.3) | 4.2 (1.0) | ND | 4.1 (3.1) |
24 | 4.6 (0.7) | 3.7 (1.3) | ND | 3.7 (2.7) |
36 | 4.0 (1.3) | 3.0 (0.7) | ND | 2.6 (1.9) |
48 | ND | 2.4 (0.9) | ND | 2.2 (1.7) |
60 | ND | 1.9 (0.4) | ND | 1.9 (1.3) |
72 | ND | 1.5 (0.5) | ND | 1.3 (1.2) |
84 | ND | 1.2 (0.3) | ND | 1.2 (1.0) |
96 | ND | 1.0 (0.3) | ND | 1.0 (0.8) |
108 | ND | 0.8 (0.4) | ND | 0.7 (0.7) |
264 | ND | 0.1 (0.1) | ND | ND |
ND, not detected.