Table 1

Statistical analysis of CYP3A inhibition at various protein concentrations by antifungal inhibitors

Regression Model	Step	Clotrimazole		Ketoconazole		Fluconazole
Regression Model	Step	r²	P	r²	P	r²	P
First Analysis:
Protein Conc.	1	0.60	0.001	0.39	0.006	0.06	0.388^1-a
+ Inhibitor Conc.	2	0.81	0.003	0.94	0.001	0.96	0.001
Second Analysis:
Inhibitor Conc.	1	0.21	0.085^1-a	0.55	0.001	0.90	0.001
+ Protein Conc.	2	0.81	0.001	0.94	0.001	0.96	0.001

Predictor (protein and inhibitor concentrations) and response (percent inhibition) variables were log transformed. Stepwise linear regression was performed using SPSS Version 7.5 (SPSS Inc., Chicago, IL).
↵1-a Non-significant, p > .05.