Comparison of the inhibitory effect of different xanthates on the activities of P-450s 1A1 and 2B1
| Xanthate | IC50 for 1A1 | IC50 for 2B1 | Ratio 1A1/2B1 |
|---|---|---|---|
| μM | |||
| C2 | 7.9 mM | 63 | 125 |
| C3 | 13 mM | 31 | 432 |
| C8 | 3 mM | 7.2 | 416 |
| C14 | 4.3 μM | 2.5 | 1.7 |
| C20 | 26 μM | 5.4 | 4.7 |
Assay conditions were as described in Experimental Procedures. The data shown represent the mean from three different experiments.