Table 1

Enzyme kinetics for dehydrogenation of 3-methylindole

Enzymes	V_max	K_m	V_max/K_m	Other Substrates	cDNA Sources
	nmol/nmol P-450/min	mM
Goat lung
microsomes^1-a	8.7	0.06	143
CYP2F1	1.3^1-b	0.018^1-b	65	Naphthalene	Human lung
CYP2F2^1-c				Naphthalene	Mouse lung
CYP2F3^1-d	0.55	0.34	1.6	Naphthalene	Goat lung

↵1-a Values from Skiles and Yost, 1996.
↵1-b These are apparent kinetic constants, based on rates observed at substrate concentrations less than 0.3 mM.
↵1-c Naphthalene oxidation demonstrated in Ritter et al., 1991.
↵1-d Values from Wang et al., 1998.