Table 2

Effects of prenylated flavonoids on the mutagenicity of IQ(6 ng/plate) activated by cDNA-expressed human CYP1A2 in Salmonella typhimurium TA98

TreatmentFlavonoid ConcentrationNumber of Revertants per plate2-a
nmol/ml top agar
Control (ethanol)03059  ± 387
8PN2191  ± 30.92-b (93.8)
104.7  ± 4.72-b (99.9)
XN21579  ± 82.32-b (48.4)
10364  ± 43.22-b (88.1)
IX2499  ± 4.92-b (83.7)
10189  ± 9.82-b (93.8)
  • 2-a  Values are means ± S.E. of triplicate plates and have been corrected for spontaneous revertants (58 ± 10). Values in parentheses are percent inhibition as compared with control.

  • 2-b  P < .05 versus control (Student's t test).