Characteristics of the control paired-fed and CRF rats
| Control Paired-Fed | CRF | |
|---|---|---|
| Body weight (g) | 385 ± 19 | 348 ± 8 |
| Serum creatinine (μmol/l) | 53 ± 3 | 152 ± 131-a |
| Serum urea (mmol/l) | 6.4 ± 1.1 | 25.3 ± 2.51-a |
| Creatinine clearance (μl/100 g b. wt./min) | 370 ± 33 | 75 ± 171-a |
| Liver total CYP450 content (nmol/mg protein) | 0.56 ± 0.02 | 0.34 ± 0.041-a |
Data are the mean ± S.E.M. Measurements were made 41 days after the first surgery.
↵1-a P < .01 compared with control paired-fed animals.