Table 4

Correlation among inhibition responses

Part A. Correlation Coefficients of the Percent Inhibition at 10 μM Inhibitor
SubstrateBQBFCDBFNFTSMDZ
BzRes0.540.680.490.510.630.76
BQ0.850.840.780.930.90
BFC0.800.670.810.88
DBF0.710.900.89
NF0.760.78
TS0.84
Part B. Correlation Coefficients of the IC50 and IC33 Values
SubstrateBzRes IC50BQ IC33BQ IC50DBF IC33DBF IC50BFC IC50
BzRes IC33 0.980.670.700.76
BzRes IC50 0.150.570.64
BQ IC33 0.900.710.99
BQ IC50 0.670.90
DBF IC33 0.870.69
DBF IC50 0.74
Part C. Correlation Coefficients of the Log Transformed IC50 and IC33 Values
SubstrateBzRes IC50BQ IC33BQ IC50DBF IC33DBF IC50BFC IC50
BzRes IC33 0.990.770.770.87
BzRes IC50 0.660.770.86
BQ IC33 0.970.910.95
BQ IC50 0.880.94
DBF IC33 0.990.93
DBF IC50 0.93