Pharmacokinetic parameters of BVU (37 μmol dose t.i.d.) in humans
| Fa | 1 (assumed) | ||
| k a | 0.01/min−1a | Ogiwara et al., 1990 | |
| Q | 1610 ml/min | ||
| K p | 1 (assumed) | ||
| fb | 0.24 | fb = fu/RB, RB = 1 was assumed. | |
| CLint | 80 ml/min4-a | Ogiwara et al., 1990 | |
| Vliver | 2800 ml | ||
| Vpv | 70 ml | ||
| Vsys | 33,000 ml4-a | Ogiwara et al., 1990 |
↵4-a Calculated by equations 9-12 to fit the reported blood concentration (Ogiwara et al., 1990).