Table 4

Summary of pharmacokinetic parameters of sulfonamides

DosefpImaxka · D · Fa/Qh4-aIu4-b
g μM μM μM
Sulfaphenazole0.50.324-c 77.94-c 7.1027.2
Sulfadiazine10.354-d 2004-e 250158
Sulfamethizole10.144-f 2224-g 23163.4
Sulfisoxazole20.234-h 9354-i 468322
Sulfamethoxazole10.354-h 2174-i 244161
Sulfapyridine10.224-d 2234-h 251104
Sulfadimethoxine10.104-d 1934-i 20139.4
Sulfamonomethoxine10.434-j 3794-j 224259

  • ↵4-a See details in the text.

  • ↵4-b Calculated by eq. 3.

  • ↵4-c Ueda et al., 1972.

  • ↵4-d Horstmann et al., 1961.

  • ↵4-e Böhni et al., 1969.

  • ↵4-f Weinstein et al., 1960.

  • ↵4-g Lumholtz et al., 1975.

  • ↵4-h Wing and Miners, 1985.

  • ↵4-i Vree et al., 1990b.

  • ↵4-j Vree et al., 1990c.