Table 4

Effect of chemicals on the expression of specific CYP mRNAs

Chemical Inducer AdministeredMajor CYP Isoform(s) Up-Regulated
3MCCYP1A1, CYP1A2
PBCYP2B1, CYP2B2
ISOCYP2E1
PCNCYP3A1, CYP3A23, CYP3A2
CLOCYP4A1, CYP4A2, CYP4A3