Table 2

AUC (0–24 h) for verapamil and metabolites in older and younger male subjects

Measured SpeciesOlder N = 11Younger N = 8
Mean ± S.D. (ng/ml · h−1)
Verapamil2815  ± 7332-150 1639  ± 466
Norverapamil2927  ± 655** 2143  ± 471
D-6172386  ± 7721894  ± 418
D-620897  ± 366757  ± 104
  • 2-150P < .0007; ** P < .007.