AUC (0–24 h) for verapamil and metabolites in older and younger male subjects
Measured Species | Older N = 11 | Younger N = 8 |
---|---|---|
Mean ± S.D. (ng/ml · h−1) | ||
Verapamil | 2815 ± 7332-150 | 1639 ± 466 |
Norverapamil | 2927 ± 655** | 2143 ± 471 |
D-617 | 2386 ± 772 | 1894 ± 418 |
D-620 | 897 ± 366 | 757 ± 104 |
↵2-150 P < .0007; ** P < .007.