Table 3

Signals (arbitrary units) obtained from the DNA arrays for the various transporters

	Gene	Controls (n = 10)		MS Baseline (n = 10)		MS Post-IFN (n = 10)		P Value
	Gene	Mean	CV	Mean	CV	Mean	CV	Disease Effect	IFN Effect
			%		%		%
MDR 1		2.9 × 10²	28	3.0 × 10²	40	2.9 × 10²	44	.90	.80
MDR 3	PGY3	3.6 × 10²	50	2.7 × 10²	50	3.8 × 10²	64	.32	.037
MDR-associated protein 1	MRP1	5.2 × 10³	33	5.3 × 10³	34	6.2 × 10³	27	.96	.088
MDR-associated protein homolog-3	MRP3	3.6 × 10²	76	3.2 × 10²	106	2.9 × 10²	88	.82	.42
MDR-associated protein homolog-5	MRP5	1.0 × 10²	33	8.0 × 10¹	62	8.8 × 10¹	49	.35	.57
Creatine transporter		1.2 × 10⁴	45	1.4 × 10⁴	35	1.2 × 10⁴	48	.30	.024
NBMPR-insensitive nucleoside transporter	ENT2	1.8 × 10³	14	1.8 × 10³	28	1.8 × 10³	18	.88	.87
X-linked PEST-containing transporter	XPCT	5.4 × 10³	24	5.1 × 10³	27	5.9 × 10³	29	.40	.089
Neutral amino acid transporter B		4.0 × 10³	61	2.9 × 10³	47	3.3 × 10³	62	.95	.420
Monocarboxylic acid transporter	SLC16A1	3.6 × 10³	15	3.6 × 10³	23	3.8 × 10³	18	.61	.35
Putative monocarboxylate transporter	MCT	2.3 × 10³	82	2.0 × 10³	94	2.1 × 10³	72	.63	.78
Na/Cl-dependent betaine transporter		2.1 × 10⁴	41	2.1 × 10⁴	35	2.3 × 10⁴	40	.71	.20
Amiloride-sensitive Na⁺/H⁺antiporter	SLC9A1	4.8 × 10³	98	6.3 × 10³	77	7.5 × 10³	84	.71	.18
Tetracycline transporter-like protein		1.0 × 10⁴	16	1.1 × 10⁴	27	1.1 × 10⁴	23	.074	.50