Specificity of monoclonal antibodies to expressed isoforms of the P450 2C subfamily as measured by ELISA
| mAb/P450 | 2C8 | 2C9*1 | 2C9*2 | 2C9*3 | 2C18 | 2C19 | 1A1, 1A2, 2A6, 2B6, 2D6, 2E1, 3A4, 3A5 |
|---|---|---|---|---|---|---|---|
| mAb 763-15-5 | 0.03-a | 1.5 | 1.82 | 1.01 | 0.0 | 0.0 | 0.0 |
| mAb 763-15-20 | 0.8 | 0.4 | 0.6 | 0.4 | 0.0 | 0.0 | 0.0 |
| mAb 592-2-5 | 0.0 | 0.83 | 1.01 | 0.92 | 0.4 | 0.0 | 0.0 |
| mAb 327-8-3 | 0.0 | 0.80 | 1.52 | 1.00 | 0.8 | 0.0 | 0.0 |
| mAb 5-7-5 | 0.0 | 0.95 | 1.13 | 1.13 | 0.67 | 1.09 | 0.0 |
| mAb 292-2-3 | 0.0 | 0.13 | 1.98 | 0.10 | 0.0 | 0.0 | 0.0 |
| mAb 1-68-11 | 0.6 | 0.78 | 0.64 | 0.72 | 0.55 | 0.75 | 0.0 |
↵3-a Values (±0.05) equal absorbance at 405 nm and have been corrected for background.