Table 4

IC50 values for the inhibition of FNTZ hydroxylation by ketoconazole

LiverIC50 Value: 3-OH FNTZ
μM
HLM10.04
HLM20.16
HLM30.12
HLM50.13
Mean4-a 0.11
S.E.4-b 0.02
  • HLM, human liver microsomes.

  • 4-a  Mean, arithmetic mean of four different human livers.

  • 4-b  S.E., standard error of four different human livers.