Kinetic rate constants for metabolism of XN in rat liver microsomes
| Substrate | Vmax | Km | Vmax/Km | R2 |
|---|---|---|---|---|
| nmol/min/nmol P450 | μM | |||
| M1 | 0.0072 ± 0.0005 | 20.16 ± 8.81 | 0.0004 | 0.98 |
| M2 | 0.0911 ± 0.0077 | 118.97 ± 38.66 | 0.0008 | 0.99 |
| M3 | 0.0035 ± 0.0006 | 246 ± 116.39 | 0.00001 | 0.97 |
| XN | 1.46 ± 0.119 | 407.36 ± 79.48 | 0.004 | 0.99 |