Summary of statistical analysis of concentrations of nicotine, cotinine, and nornicotine in brain and blood across 1 to 10 intermittent, peripheral [2′-14C]nicotine injections
| Intermittent Injections | |
|---|---|
| Overall ANOVA for concentration | Compound × biological sample × number of injections interaction (F (8,28) = 5.61, p < 0.01) |
| ANOVA of nicotine concentration | Number of injections × biological sample interaction (F (3.8) = 5.52,p < 0.05) |
| ANOVA of cotinine concentration | Main effect of number of injections (F (3.8) = 122.53,p < 0.001) |
| ANOVA of nornicotine concentration | Number of injections × biological sample Interaction (F (3.8) = 25.89, p < 0.001) |
| Overall ANOVA for brain/blood ratio | Number of injections × compound interaction (F (6.15) = 6.64,p < 0.01) |