Table 5

Calculation of scaling factors for compound B

Organ Weight (A)5-aSlice Weight (B)Fraction Metabolized (C)5-b(A/B) · CScaling Factor
g mg
Liver15.3140.262840.98
Lung6.930<0.0100
Kidney2.9140.0360.02
Small intestine7.22000

  • ↵5-a  Derived from de Kanter et al. (2002).

  • ↵5-b  Data from Table 2.