Table 6

Calculation of scaling factors for compound C

Organ Weight (A)6-aSlice Weight (B)Fraction Metabolized (C)6-b(A/B) · CScaling Factor
g mg
Liver15.3140.374040.41
Lung6.930<0.0100
Kidney2.914<0.0100
Small intestine7.220.165760.59
  • 6-a  Derived from de Kanter et al. (2002).

  • 6-b  Data from Table 2.