The expression of various cytochrome P450 mRNA in lymphocytes from 37 healthy adult volunteers before and after oral rifampin administration (600 mg once daily in the evening for 7 days)
| Enzyme mRNA | Baseline Frequency | After Rifampin Administration |
|---|---|---|
| CYP2C8 | 35 | 35 |
| CYP2C9 | N.D. | N.D. |
| CYP2E1 | 15 | 29 |
| CYP3A4 | N.D. | N.D. |
| CYP3A5 | 11 | 13 |
| CYP3A7 | 9 | 20 |
| CYP4A11 | 22 | 27 |
| CYP4B1 | 7 | 7 |
| MDR1 | 37 | 37 |
N.D., not detected.