Table 4

Summary of the correlation of clearances obtained from fresh and EHS sandwich gel versus clearances obtained from cryopreserved hepatocytes

Cryopreserved HepatocytesR2(Fresh Hepatocytes)R2(Sandwich-Cultured Hepatocytes)
RatDogMonkeyRatDogMonkey
Rat0.7690.770
Dog0.8170.716
Monkey0.6990.583