1H Chemical shifts of key protons in the heptanoic/heptenoic acid side chain of all three statins and their corresponding glucuronides
Position | SVA | SVA Glucuronide | CVA | CVA Glucuronide | AVA | AVA Glucuronide |
---|---|---|---|---|---|---|
2 | 2.28, 2.38 | 2.46, 2.60 | 2.34, 2.39 | 2.53, 2.54 | 2.31, 2.38 | 2.46, 2.55 |
3 | 4.19 | 4.14 | 3.67 | 3.64 | 4.01 | 4.08 |
5 | 3.58 | 3.56 | 4.18 | 4.19 | 3.68 | 3.78 |
1‴ | 5.48 | 5.57 | 5.53 |
All chemical shifts are referenced to residual CD2HCN at 1.99 ppm.